So you've decided to donate a kidney. The remaining recipients spent a median of 11 months on dialysis prior to transplantation. The factors that were adjusted for include recipient age, recipient sex, recipient Charlson comorbidity index, dialysis duration, peak panel reactive antibody (PRA), donor age, donor sex, laparoscopic or open surgery, donor-recipient relationship and year of transplant. Recipients were also assessed using an eGFR cut-point of 80 mL/min per 1.73 m2 (referent: ≥80 mL/min per 1.73 m2). Transplant outcomes for recipients comparing varying categories of baseline eGFR (reference group: ≥110 mL/min per 1.73 m2 for all comparisons). This is an official U.S. Government Web site managed by the Health Resources and Services Administration, U.S. Department of Health & Human Services. This potential for misclassification may explain the lack of difference observed in recipient outcomes, and may not generalize to patients with sustained borderline low GFR assessed via various techniques. U.S. Department of Health and Human Services, Health Resources and Services Administration. Association Between Midlife Physical Activity and Incident Kidney Disease: The Atherosclerosis Risk in Communities (ARIC) Study. h�b```f``���d�3�0 �P�����c*C#�m����՞��� lA��78�eڣ�m"C��G@M��U�6>_Tơ� 3��;`��m The opinions, results, and conclusions reported in this paper are those of the authors, and are independent of the funding sources, the Ministry of Health and Long-Term Care and Trillium Gift of Life Network. Page Last Updated: 20th May 2009. Published by Oxford University Press on behalf of ERA-EDTA. aIncludes 367 recipients of pre-emptive living donor kidney transplants (i.e. /MҞ�9�뇋�3�t*�Rݘu�ֶ��{y�xV�`�m�����Nv;�:4O�þ��?�� In the context of baseline donor renal function, this study found that graft survival after receipt of a kidney from a living donor with an eGFR < 80 mL/min per 1.73 m2 was no different than when the kidney came from a living donor with a higher eGFR. If diabetes or hypertension statuses are unknown, the calculator will assume the donor has the same chance as a randomly selected donor having the condition. We comply with the HONcode standard for trustworthy health information: The wait for a deceased donor could be 5 years, and in some states, it is closer to 10 years." The numbers are familiar, but they are still no less staggering. Historically, the kidney allocation system has used two designations to describe kidneys; they are either from a standard criteria donor (SCD) or an expanded criteria donor (ECD). And, of course, the issue of donor health (which is beyond the scope of this particular study) must always be considered prior to liberalizing any selection criteria [30], particularly for younger donors who may expect to live many decades with one kidney. This website is for informational purposes only and DOES NOT CONSTITUTE THE PROVIDING OF MEDICAL ADVICE. h��XYo�8�+��Ţ�:�"�c�����m�k�A��X�-���&��;CJ���q�mX�9I~���gJ�L���L(lK�d���L�K�L`���c, ��e�"N|��˘�$e���`�dP�i�(&$�SJc[J������B&�"�+�*��p��h�1(G��LВI��Z1i���f2h��*�I�h���P�iMf�t�Q�2�iC=F0�D�:Hlӑ�X Q��q�f ��=� In 2005, a survey of transplant programmes done by Mandelbrot et al. Similar results were observed when dichotomizing the baseline donor eGFR using a cut-point of 80 mL/min per 1.73 m2—adjusted HR 1.01 [95% confidence interval (95% CI) (0.76–1.44)]. Are You Really Listed On The Kidney Transplant Waiting List Or Do You Just Think You Are? Please check for further notifications by email. Baseline donor GFR was estimated using the Chronic Kidney Disease Epidemiology (CKD-EPI) Collaboration equation based on the serum creatinine measured during the living donor assessment [10]. Recipient characteristics by donor eGFR at the time of transplantation. A medical doctor should always assist you in making any treatment decisions and patients should always be under the care and supervision of a physician. All analyses were conducted using SAS version 9.2 (SAS Institute, Inc., Cary, NC, USA) and R version 2.15.1 (R Foundation for Statistical Computing, Vienna, Austria). All rights reserved. As expected, estimates of GFR were consistently higher using the CKD-EPI equation than with the MDRD equation at the levels of renal function studied.