The clinical impact of cytomegalovirus infection following allogeneic hematopoietic cell transplantation: Why the quest for meaningful prophylaxis still matters. Medicines are given before the transplant to help lessen your risk of side effects and reaction to the preservatives that are used when freezing the stem cells (in autologous transplants only). The length of time varies with the number of stem cells being given. COVID-19 is an emerging, rapidly evolving situation. 2018 Nov 22;9:2734. doi: 10.3389/fimmu.2018.02734. Browsing activity is recorded to form aggregate and anonymous demographic information, which is used as described above. Front Immunol. Neuenhahn M, Albrecht J, Odendahl M, Schlott F, Dössinger G, Schiemann M, Lakshmipathi S, Martin K, Bunjes D, Harsdorf S, Weissinger EM, Menzel H, Verbeek M, Uharek L, Kröger N, Wagner E, Kobbe G, Schroeder T, Schmitt M, Held G, Herr W, Germeroth L, Bonig H, Tonn T, Einsele H, Busch DH, Grigoleit GU. Usually a combination of chemotherapy drugs is given. There are a few steps to get a stem cell transplant. Gainesville, Florida, Jayesh Mehta, MD Radiation therapy is given to the entire body. Identify risk factors for CMV disease in HSCT recipients, Describe the direct and indirect effects of CMV infection, Outline clinical considerations in late CMV disease, Cite current and emerging therapies for CMV prevention and treatment. Theobald SJ, Khailaie S, Meyer-Hermann M, Volk V, Olbrich H, Danisch S, Gerasch L, Schneider A, Sinzger C, Schaudien D, Lienenklaus S, Riese P, Guzman CA, Figueiredo C, von Kaisenberg C, Spineli LM, Glaesener S, Meyer-Bahlburg A, Ganser A, Schmitt M, Mach M, Messerle M, Stripecke R. Front Immunol. Your body will also have this odor. USA.gov. Expert commentary: Despite advances in diagnostic tests and treatment, there is still room for refining management of CMV in HSCT recipients. The information is not shared with others for commercial purposes, unless the user has granted prior permission. Donor-derived, pathogen-specific T cells adoptively transferred after transplantation could contribute to reduce the impact of CMV infection on patient's outcome. Expiration date: April 30, 2010 HHS By participating in the Web-based activity, you agree that Carden Jennings Publishing has full permission to provide this minimum subset of information to third parties as required by law. Della Chiesa M, De Maria A, Muccio L, Bozzano F, Sivori S, Moretta L. Front Microbiol. Carden Jennings Publishing and the Medical College of Wisconsin present this resource for educational purposes only. This is called total body irradiation (TBI). Killer Ig-Like Receptors (KIRs): Their Role in NK Cell Modulation and Developments Leading to Their Clinical Exploitation. 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