To date, over 2500 Salmonella serotypes have been identified and more than half of them belong to Salmonella enterica subsp. Salmonella is one of the most frequently isolated foodborne pathogens. The emergence of multi-drug-resistant (MDR) Salmonella serotypes is having a great impact on the efficacy of antibiotic treatment, and an increasing prevalence of MDR strains may lead to an increase in mortality rates of Salmonella infections. METHODS: A population-based prospective surveillance design was used. H-50001-A000027) awarded to K-GC and external industry grants from Biotek Abadi Sdn Bhd (vote no. The development of multi-drug resistance in the serotypes of Salmonella has a significant impact on the antibiotic treatment of Salmonella infections. Background Preventive measures have been proposed to eliminate the spread of Salmonella infection. We believe there will be difference, The main aim is to set up a centralised repository or database for all data from whole genome sequencing, whole exome sequencing, transcriptome sequencing, microbiome sequencing and methylome analy, Salmonella is one of the most frequently isolated food-borne microorganism. During induction with multi-stress conditions, nutrition starvation antagonizes with low-level acidity. Salmonella is one of the most frequently isolated foodborne pathogens. Epidemiological studies indicate that MDR Salmonella serotypes are more virulent than susceptible strains, as reflected by increased severity and more prolonged disease in patients infected by MDR strains. Gastroenteritis is the most common Salmonella infection worldwide, accounting for 93.8 million cases which result in 155,000 deaths per year (Majowicz et al. 10.1080/21553769.2015.1051243https://doi.org/10.1080/21553769.2015.10512432015-06-09truewww.tandfonline.com10.1080/21553769.2015.1051243www.tandfonline.comtrue2015-06-0910.1080/21553769.2015.1051243 In general, interventions to improve the microbial quality of drinking water are effective in preventing diarrhoea. Inactive parenteral and oral live attenuated vaccines are the two types of vaccine currently approved for the prevention of enteric fever. This phenomenon has raised concern among public health authorities regarding both clinical management and prevention of the infection (Crump et al. 2011). The annual typhoid incidence (per 100 000 person years) among this age group varied from 24.2 and 29.3 in sites in Viet Nam and China, respectively, to 180.3 in the site in Indonesia; and to 412.9 and 493.5 in sites in Pakistan and India, respectively. 2002). 2006). 2006). 11:859–867. In the early 1960s, the first incidence of Salmonella resistance to a single antibiotic, namely chloramphenicol, was reported (Montville & Matthews 2008). This review further highlights the antimicrobial resistance trends of non-typhoidal Salmonella isolates at the human–food interface, with a focus on clinically important antimicrobials in humans, by collating evidence from previous investigations in Australia. 1990). s in the mutational profiles of our patients compared to the Caucasian populations. Similar to enteric fever, high fever is the characteristic symptom of bacteraemia, but without the formation of rose spots as observed in patients with enteric fever. The major reasons for wanting more children for those who already had some were; the sex of the children (wanting to have both girls and boys and especially boys), desire for large families, pressure from family, and getting new partners. salamae; IIIa, S. enterica subsp. elegans). All children registered fever's main complaint (100%). The Other extraintestinal complications include cellulitis, urinary tract infections, pneumonia, endocarditis and meningitis (Shimoni et al. The majority of the gene cassettes located within these plasmids consist of resistance genes that confer the antimicrobial resistance property of the serotypes against traditional antibiotics such as chloramphenicol, tetracycline, ampicillin and streptomycin (Guerra et al. pediatric unit, from April 1, 2017 to April 31, 2019, over a 24 month period.