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In 2019, Avexis's first gene therapy drug onasemnogene abeparvovec (Zolgensma®) received regulatory approval in the United States and has a list price of USD 2.125 million per injection, becoming the most expensive drug in the world. The departure of Brian and Allan Kaspar is notable, as both played significant roles at AveXis, which Novartis bought last year for $8.7 billion. Competitors of AveXis include Kolon TissueGene, Arbutus Biopharma and Aptamer Group. 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